There might be a few contraindications for Tadalafil, such as the reality you are taking nitrate medication or the truth you have actually been suggested to refrain from sexual activity to stay clear of placing as well much stress on your heart. Consuming grapefruit juice is also not advised as it can induce some possibly harmful communications with TADALAFIL. Inform your physician if you have pre-existing eye issues, high blood stress, cigarette smoking, cardiovascular disease, diabetes, higher cholesterol, or more than FIFTY years old, as those might be the danger factors of a major but rare negative side effects - unexpected vision loss.